It looks like our hwh parsing is getting confused by an IP with two AXI slave ports. Would you be able to share your hwh file so we can add it to our test suite?
You can instantiate the pynq.Interrupt class directly by passing it the name of the pin - "BERT_0/event_irq" in your case. Note that PYNQ can only interrupt with interrupts that ultimately attach to IRQ line 0 so this still may not work in your example. You can either move the interrupts around or change the UIO entry in device-tree to point to correct interrupt line - that should work but we haven’t tested it.
Peter