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Hoping this post will show some promise.

Did you also run into this problem building the pynq image yourself and then resort to using the prebuilt one: Cant run on ubuntu since "can't install both gcc-multilib and gcc-arm-linux" · Issue #6 · sarafs1926/ZCU216-PYNQ · GitHub

Will make sure to post here if I can figure either of these 2 problems out