I am using PYNQ with ZCU111 RFSOC board. I can reprogram the LMX2594 external PLL using the SDK baremetal drivers. However I have never succeeded in progamming the LMX2594 from PYNQ Pyhton drivers. I have taken one the of the standard demo designs and output each of the DAC and ADC clocks from the rf_data_converter IP. I divide the clocks by 16 (using BUFGCE and a flop ) and output the signals via J10 of the extender board. Thus I can “see” the adc and dac clocks. If I try and use the LMX2594 clock configuration routines from the PYNQ library the adc and dac clocks die.